Pathway
Pathogenic IgG (IdeS cleavage)
Many autoimmune diseases are driven by harmful IgG antibodies. The bacterial enzyme IdeS (imlifidase) cleaves circulating IgG within hours, rapidly removing the autoantibody burden in acute, antibody-mediated disease such as anti-GBM.
1
Drugs
1
Trials tracked
0
Resolved
1
Indications
Drugs hitting this target
Trials targeting IgG / IdeS
1 benchmarkIndications
About IgG / IdeS
What is IgG / IdeS?
Many autoimmune diseases are driven by harmful IgG antibodies. The bacterial enzyme IdeS (imlifidase) cleaves circulating IgG within hours, rapidly removing the autoantibody burden in acute, antibody-mediated disease such as anti-GBM.
Which drugs target IgG / IdeS?
Therapies acting on IgG / IdeS tracked here include Imlifidase.