GeneGene: FCGRT
Neonatal Fc receptor (FcRn)
FcRn (encoded by FCGRT) recycles IgG antibodies and extends their half-life. Blocking FcRn accelerates the clearance of pathogenic IgG autoantibodies, a mechanism used to treat antibody-mediated autoimmune diseases such as thyroid eye disease and myasthenia gravis.
1
Drugs
1
Trials tracked
0
Resolved
1
Indications
Drugs hitting this target
Trials targeting FcRn
1 benchmarkIndications
About FcRn
What is FcRn?
FcRn (encoded by FCGRT) recycles IgG antibodies and extends their half-life. Blocking FcRn accelerates the clearance of pathogenic IgG autoantibodies, a mechanism used to treat antibody-mediated autoimmune diseases such as thyroid eye disease and myasthenia gravis.
Which drugs target FcRn?
Therapies acting on FcRn tracked here include Efgartigimod.