GeneGene: CTSC
Dipeptidyl peptidase-1 (DPP1 / cathepsin C)
DPP1 (cathepsin C, encoded by CTSC) activates neutrophil serine proteases that drive tissue-damaging inflammation. Reversible DPP1 inhibition lowers active neutrophil elastase, an approach validated in bronchiectasis and explored in other neutrophilic diseases.
1
Drugs
1
Trials tracked
0
Resolved
1
Indications
Drugs hitting this target
Trials targeting DPP1
1 benchmarkIndications
About DPP1
What is DPP1?
DPP1 (cathepsin C, encoded by CTSC) activates neutrophil serine proteases that drive tissue-damaging inflammation. Reversible DPP1 inhibition lowers active neutrophil elastase, an approach validated in bronchiectasis and explored in other neutrophilic diseases.
Which drugs target DPP1?
Therapies acting on DPP1 tracked here include Brensocatib.