GeneGene: RBP4
Retinol-binding protein 4 (RBP4)
RBP4 is the serum carrier that delivers vitamin A (retinol) from the liver to peripheral tissues, including the eye. Lowering circulating RBP4 reduces the retinal delivery of vitamin A and the formation of the toxic byproducts implicated in Stargardt disease and dry AMD.
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Drugs
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Trials tracked
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Resolved
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Indications
Drugs hitting this target
Trials targeting RBP4
1 benchmarkIndications
About RBP4
What is RBP4?
RBP4 is the serum carrier that delivers vitamin A (retinol) from the liver to peripheral tissues, including the eye. Lowering circulating RBP4 reduces the retinal delivery of vitamin A and the formation of the toxic byproducts implicated in Stargardt disease and dry AMD.
Which drugs target RBP4?
Therapies acting on RBP4 tracked here include Tinlarebant.