GeneGene: ATR

ATR kinase

ATR is a master kinase of the DNA-damage response that lets tumor cells survive replication stress. ATR inhibitors aim to overwhelm cancer cells with unrepaired damage and, in combination with immunotherapy, to make tumors more visible to the immune system.

1
Drugs
1
Trials tracked
0
Resolved
1
Indications

Drugs hitting this target

Trials targeting ATR

1 benchmark

Indications

About ATR

What is ATR?

ATR is a master kinase of the DNA-damage response that lets tumor cells survive replication stress. ATR inhibitors aim to overwhelm cancer cells with unrepaired damage and, in combination with immunotherapy, to make tumors more visible to the immune system.

Which drugs target ATR?

Therapies acting on ATR tracked here include Ceralasertib.

References